Tectorigenin 7-O-β-D-glucopyranoside
Tectoridin
CAS: 611-40-5
Molecular Formula: C22H22O11
Tectorigenin 7-O-β-D-glucopyranoside - Names and Identifiers
| Name | Tectoridin |
| Synonyms | Shekkanin Tectoridin TectoridinI TECTORIDIN (RG) Tectorigenin 7-glucoside Tectorigenin 7-O-β-D-glucopyranoside Tectoridin [Tectorigenin 7-glucoside, Shekanin] D-Glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside 5-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one |
| CAS | 611-40-5 |
| InChI | InChI=1/C22H22O11/c1-30-21-13(32-22-20(29)19(28)17(26)14(7-23)33-22)6-12-15(18(21)27)16(25)11(8-31-12)9-2-4-10(24)5-3-9/h2-6,8,14,17,19-20,22-24,26-29H,7H2,1H3/t14-,17-,19+,20-,22-/m1/s1 |
Tectorigenin 7-O-β-D-glucopyranoside - Physico-chemical Properties
| Molecular Formula | C22H22O11 |
| Molar Mass | 462.4 |
| Density | 1.609±0.06 g/cm3(Predicted) |
| Melting Point | 256-258° |
| Boling Point | 798.1±60.0 °C(Predicted) |
| Specific Rotation(α) | D20 -29.4° (pyridine) |
| Flash Point | 279.7°C |
| Solubility | Soluble in methanol |
| Vapor Presure | 7.19E-27mmHg at 25°C |
| Appearance | Needle crystal |
| Color | White to Almost white |
| pKa | 6.10±0.20(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.694 |
| MDL | MFCD04039835 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, derived from belamcaria, Iris. |
| In vitro study | Tectoridin scarcely binds to ER alpha as compared to 17beta-estradiol and genistein. Tectoridin induceds potent estrogenic effects, namely recovery of the population of cells in the S-phase after serum starvation, transactivation of the estrogen response element, and induction of MCF-7 cell proliferation. Tectoridin induces estrogenic effect, and this effect is severely abrogated by treatment with U0126 ( MEK1/2 inhibitor). Tectoridin promotes phosphorylation of ERK1/2, but does not affect phosphorylation of ER alpha at Ser (118). It also increases cellular accumulation of cAMP. |
Tectorigenin 7-O-β-D-glucopyranoside - Risk and Safety
| WGK Germany | 3 |
| RTECS | DJ3090000 |
| HS Code | 29389090 |
Tectorigenin 7-O-β-D-glucopyranoside - Reference
| Reference Show more | 1. Zeng Huiting, Chen Chao, Yan Huailiang, etc. Chemical composition analysis of flavonoids in the waste of Pueraria resources industrialization process [J]. China Pharmacy, 2020, v.31;No.670(04):72-77. 2. Valkω, Kl · ra. "Application of high-performance liquid chromatography based measurements of obesity to model biological distribution." Journal of chromatography A 1037.1-2 (2004): 299-310.https:// doi.org/10.1016/j.chroma.2003.10.084 3. Valkω, Kl · ra. "Application of high-performance liquid chromatography based measurements of obesity to model biological distribution." Journal of chromatography A 1037.1-2 (2004): 299-310.https://doi.org/10.1016/j.chroma.2003.10.084 4. [IF=4.411] Jifeng Gu et al."Application of High-Performance Liquid Chromatography Coupled with Linear Ion Trap Quadrupole Orbitrap Mass Spectrometry for Qualitative and Quantitative Assessment of Shejin-Liyan Granule Supplements."Molecules. 2018 Apr;23(4):884 5. [IF=3.645] Wenjie Wu et al."Simple, rapid and environmentally friendly method for the separation of isoflavones using ultra-high performance supercritical fluid chromatography."J Sep Sci. 2017 Jul;40(13):2827-2837 6. [IF=6.922] Zhen-Hua Ying et al."Iridin Prevented Against Lipopolysaccharide-Induced Inflammatory Responses of Macrophages via Inactivation of PKM2-Mediated Glycolytic Pathways."J Inflamm Res. 2021; 14: 341-354 7. [IF=4.769] Jing Han et al."Qualitative and quantitative evaluation of Flos Puerariae by using chemical fingerprint in combination with chemometrics method."J Pharm Anal. 2021 Sep;: 8. [IF=4.759] Wenjie Wu et al."An analytical strategy for accurate, rapid and sensitive quantitative analysis of isoflavones in traditional Chinese medicines using ultra-high performance supercritical fluid chromatography: Take Radix Puerariae as an example."J Chromato 9. [IF=3.645] Ziyun Wei et al.Studies on chemical constituents of Flos Puerariae-Semen Hoveniae medicine pair by HPLC and Fourier transform ion cyclotron resonance mass spectrometry.Journal Of Separation Science.2021 Nov 06 |
Tectorigenin 7-O-β-D-glucopyranoside - Reference Information
| Application | The Herba glycoside was extracted from the rhizome of the plant of Iris family, which can be used for content determination, identification, pharmacological experiments, etc. It is also a lactate dehydrogenase (LDH) inhibitor. |
| biological activity | Tectoridin is an isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen that activates estrogen and thyroid hormone receptors. Tectoridin exerts estrogenic effects through the ER-dependent genomic pathway and the GPR30-dependent non-genomic pathway. |
| Use | belamnoside has anti-inflammatory and antibacterial effects. for content determination/identification/pharmacological experiments. Pharmacological effects: heat toxin, swelling pain. |
Last Update：2024-04-09 20:45:29
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Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Tectoridin Visit Supplier Webpage Request for quotationCAS: 611-40-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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